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Medications that inhibit CYP2D6 action, like paroxetine and quinidine, may induce decreased clearance of oxycodone which may lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in an increase in oxycodone Cmax by 11%, AUC by thirteen%, and t½ elim.These strengths may trigger overdose (even Dying) if t